▷ 3 good news from corona research

17.02.2021 – 10:13

BIOMES

Press release

3 good news from corona research

Wildau, February 17, 2021 – The SARS-CoV-2 virus has been with us for about a year. According to a recent survey, every second person suffers[1] meanwhile under a corona blues and feels at the mercy of the virus. Depressing corona news is added almost daily. But there is also news that gives hope. Current studies show: We can not only reduce the risk of infection, but also influence the course in the event of an infection. The focus is increasingly on the intestinal microbiome. The experts from the biotechnology company BIOMES summarize the latest, positive findings here.

Good News 1: Study shows link between intestinal flora balance and immune responses against COVID-19

Stop – no entry for pathogens! “If our organism reacts to unwanted viruses or bacteria by defending itself, we speak of an immune response,” explains Dr. Paul Hammer, CEO of BIOMES. “The following applies: the more effective this answer is, the lower the risk of developing symptoms or becoming seriously ill after contact.”

It is becoming increasingly clear that the intestines play a decisive role in this. “Two areas are important: firstly, the mucous membrane of the intestine, since this is where up to 80 percent of all immune cells are located, especially B cells that produce antibodies,” says systems biologist Hammer. “And secondly, the intestinal flora. If the intestinal microbiome is optimally colonized with healthy bacteria, the risk of diabetes, cardiovascular diseases and obesity is reduced. In other words, precisely for the factors that have been shown to determine the severity of a COVID-19 disease – and thus also the mortality rate[2]. ”A study recently published in the BMJ Journal Gut has been published[3], shows, among other things, that the intestinal flora is often weakened in precisely those risk groups. The results suggest: We are able to influence the course of the disease either positively or negatively with our diet and lifestyle.

But how can the microbiome be strengthened, i.e. how can the number of good bacterial strains be increased? Hammer: “The foundation is clearly the lifestyle and a balanced diet. What we eat has a direct impact on the composition of our intestinal flora – and thus the effectiveness of our immune system. ”The focus should be on intestinal-friendly and fiber-rich foods such as vegetables, fruit and whole grain products. “Dietary fibers are indigestible plant components that have long been underestimated. Today we know that they are used by the bacteria, ensure a good intestinal flora and protect against diabetes. Probiotics such as yogurt, tofu and kefir as well as fermented vegetables are also helpful. ”

Good News 2: Probiotics Can Relieve COVID-19 Symptoms and Lower the Risk of Serious Breaks

At the beginning of the pandemic, COVID-19 was primarily considered a lung disease. But it quickly became clear that SARS-CoV-2 was a Multiorgan-Virus[4] and can affect various organs. “The intestines in particular are often affected. Sick people often suffer from diarrhea, ”says Microbiologist Dr. Tewodros Debebe, scientific director at BIOMES. In a study[5]that was recently published in the trade journal Frontiers in Medicine was published, doctors divided COVID-19 patients into two groups. Both groups were treated with medication against the virus, one group also received a probiotic made up of different bacterial cultures. “The result was impressive,” said Debebe. “Because in this group, almost all patients decreased not only the intestinal complaints, but also that within 72 hours The risk of pulmonary complications was reduced 8-fold. ”Debebe hopes that these findings will be taken into account when treating people with COVID-19.

Good News 3: On the trail of the mutants

While research teams are finding out more and more about the SARS-CoV-2 virus, mutations are causing the scientists, the federal government and the Robert Koch Institute (RKI) more and more headaches. The new variant B.1.1.7. Is rampant in Great Britain, while the mutated variant B.1.351 is spreading rapidly in South Africa. Both mutants have already been detected in Germany. Researchers assume that they could be significantly more contagious than the original corona virus. It is currently largely unclear whether they lead to more serious illnesses or are more fatal. Likewise, how exactly the previously approved vaccines also work against the new variants. So far, the genome of the corona virus has hardly been examined in Germany. “But only through this particular analysis, too Genome sequencing called, mutants can be fully discovered and conclusions can be drawn about the spread, ”explains Dr. Paul Hammer. Federal Health Minister Jens Spahn (CDU) has now signed an ordinance that laboratories should also examine five to ten percent of all positive corona tests for mutants. The results are then sent to the RKI. Hammer: “This is a right and important step to get the corona virus under control in the long term.”

Editor’s note

Would you like more good corona news? Our experts are available for interviews.

[1] https://www.infratest-dimap.de/umfragen-analysen/bundesweit/umfragen/aktuell/fast-die-haelfte-der-deutschen-belasten-die-corona-auflagen-stark/

[2] https://www.aerzteblatt.de/nachrichten/119602/COVID-19-Diabetes-und-Hypertonie-erhoehen-Sterberisiko-vor-allem-bei-Komplikationen

[3] https://gut.bmj.com/content/70/2/276

[4] https://www.aerzteblatt.de/nachrichten/112987/Multiorganvirus-SARS-CoV-2-Autopsie-zeigt-Befall-zahlreicher-Organe

[5] https://www.frontiersin.org/articles/10.3389/fmed.2020.00389/full

About BIOMES NGS GmbH

The biotechnology company BIOMES uses modern biotechnological processes to study bacteria that live in and on the human body. The intestinal flora self-test INTEST.pro appeared as the first product in 2018, which is now sold internationally. To do this, the users take a small stool sample in a familiar environment and send it to the BIOMES laboratory. There, the DNA of almost all microbes in the intestinal flora is analyzed on the basis of the so-called next-generation sequencing method. A knowledge database that brings together over 7,000 scientific studies on the microbiome enables a detailed, automated interpretation of the bacterial findings. The results are personal microbiota profiles, on the basis of which customers receive individual recommendations for improving their quality of life. The analysis provides information about the proportion of beneficial and harmful bacteria, inflammation indicators, vitamins and the immune system, tendencies to intolerance, type of intestinal flora and calorie utilization. This means that the INTEST.pro intestinal flora self-test can help people with symptoms such as irritable bowel syndrome, obesity or immune deficiency to find their causes. Every customer also receives a seven-day, individual nutrition plan after purchasing the INTEST.pro. This is based on the evaluation results and is available to the customer online in the dashboard. The test is available for 139 euros at www.biomes.world/shop and from selected pharmacies and nutritionists. BIOMES NGS GmbH was founded in 2017 from an EXIST foundation at the Technical University of Wildau near Berlin. www.biomes.world

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