AstraZeneca sees high effectiveness confirmed «kleinezeitung.at

The vaccine protects against Covid-19 with an effectiveness of 76 percent – not 79 percent, the company announced Thursday morning, citing further data from a so-called Phase III study with around 32,500 test subjects.

04.57, 25 March 2021

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AstraZeneca does not come to rest, most recently a report made the rounds on Wednesday that the British-Swedish company had hidden millions of doses of Covid vaccination in Italy and hoarded them for export. The pharmaceutical company rejected this allegation. However, data problems in a phase III study in the USA also sparked discussions.

Due to updated data, AstraZeneca had to revise the effectiveness slightly downwards. The vaccine protects with an effectiveness of 76 percent – not 79 percent – before Covid-19, the company announced Thursday morning, citing further data from a so-called Phase III study with around 32,500 test subjects.

Protection against severe gradients

It is important to emphasize, however, that these three percent mean little difference for the individual. Because in relation to severe Covid courses, which also mean hospitalizations, the lie Effectiveness across all age groups at 100 percentsays the company.

For people over 65 years of age, this value is 85 percent. It means that 85 percent fewer diseases occurred among the older volunteers in a vaccinated group than those of a control group. There was still talk of 80 percent on Tuesday.

Data had to be delivered later

On Tuesday she had US health authority NIAID questioned the validity of data from a new investigation by Astrazeneca into its vaccine. AstraZeneca then agreed to deliver data within 48 hours. Earlier studies, which also speak for a good effectiveness of the preparation, the NIAID did not doubt in its statement.

More on the topic (6191c7a3)

AstraZeneca has now stated that the results of the interim analysis have been confirmed. The vaccine was well tolerated and no safety concerns related to the vaccine were identified. AstraZeneca chief researcher Mene Pangalos said it looks forward to filing an application for emergency approval in the US in the coming weeks.

The British-Swedish company has the Vaccine called AZD1222 developed together with Oxford University. It has been used on a large scale in the UK since January.

Germany and several other countries had suspended the vaccination with the Astrazeneca substance for the time being because several cases of thrombosis (blood clots) in the cerebral veins were reported in relation to the vaccination. The vaccine is now being used again. In Austria, they had waited for the decision of the European Medicines Agency (EMA) and continued vaccination. After the EMA found last week that the vaccine was “safe and effective”, the vaccination program continued unchanged.

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